Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 9/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 5/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.39 |
| ▸ | TYK2 | P29597 | 4/20 | 0.39 |
| ▸ | JAK3 | P52333 | 4/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048821 | 0.84 | TSHR (0.49) | CHEK2JAK2MEN1TSHRKMT2A | |
| SCHEMBL27852041 | 0.74 | KIF11 (0.51) | HTR1BMEN1CYP1A2HTR1ATSHR | |
| SCHEMBL8226965 | 0.73 | MAPK14 (0.53) | CHEK2ARPARP10 | |
| Terephthalamide SCHEMBL28385024 | 0.73 | PARP1 (0.50) | HTR1BMEN1CYP1A2HTR1ATSHR | |
| SCHEMBL3786947 | 0.73 | PARP10 (0.47) | CHEK2ARPARP10 | |
| SCHEMBL5394297 | 0.71 | POLB (0.50) | JAK2HTR1BMEN1CYP1A2HTR1A | |
| SCHEMBL14972617 | 0.71 | PARP10 (0.46) | CHEK2ARPARP10 | |
| SCHEMBL11810570 | 0.70 | KIF11 (0.57) | HTR1BMEN1CYP1A2HTR1ATSHR | |
| SCHEMBL3790168 | 0.70 | PARP10 (0.47) | CHEK2HSD17B10PARP10 | |
| SCHEMBL28221114 | 0.69 | CDK4 (0.43) | JAK2MEN1TSHRKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237462-B | It is a kind of that there is high flatness diamine monomer and its synthetic method and application containing carbazole structure | 湖南工业大学 | 2018-11-27 | — | — | CN | disclosed |
| CN-105482116-B | A kind of polyimide nano-composite material and its preparation method and application containing carbazole structure | 湖南工业大学 | 2018-08-07 | — | — | CN | disclosed |
| CN-105482116-A | Polyimide nanometer composite with carbazole structure and preparation method and application of polyimide nanometer composite | UNIV HUNAN TECH | 2016-04-13 | — | — | CN | disclosed |
| CN-105461925-A | Polyimide containing carbazole structure, preparation method thereof and application thereof | UNIV HUNAN TECH | 2016-04-06 | — | — | CN | disclosed |
| CN-105237462-A | Diamine monomer containing carbazole structure and having high planarity, synthetic method and application thereof | UNIV HUNAN TECHNOLOGY | 2016-01-13 | — | — | CN | disclosed |