Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195629 | 0.93 | LTA4H (0.43) | LTA4HTSHRCYP3A4TDP1CA4 | |
| SCHEMBL7615332 | 0.90 | LTA4H (0.41) | LTA4HTSHRCYP3A4TDP1CA4 | |
| SCHEMBL11664687 | 0.88 | LTA4H (0.36) | LTA4HTSHRCYP3A4TDP1CA4 | |
| SCHEMBL17189423 | 0.87 | CYP3A4 (0.43) | LTA4HTSHRCYP3A4TDP1CA4 | |
| SCHEMBL9063101 | 0.84 | CA4 (0.39) | LTA4HTSHRCYP3A4TDP1CA4 | |
| SCHEMBL11701096 | 0.82 | TSHR (0.42) | TSHRCYP3A4TDP1MAOA | |
| SCHEMBL1465968 | 0.81 | TDP1 (0.38) | LTA4HTSHRCYP3A4TDP1CA4 | |
| SCHEMBL29019209 | 0.81 | CYP3A4 (0.38) | LTA4HTSHRCYP3A4TDP1 | |
| SCHEMBL3628714 | 0.80 | LTA4H (0.33) | LTA4HTSHRCYP3A4TDP1CA4 | |
| SCHEMBL3628711 | 0.80 | LTA4H (0.33) | LTA4HTSHRCYP3A4TDP1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518761-A | Preparation method of phenanthridine compound | 遵义医学院 | 2017-03-22 | — | — | CN | claimed |
| CN-106518761-A | Preparation method of phenanthridine compound | 遵义医学院 | 2017-03-22 | — | — | CN | disclosed |
| CN-105237477-A | Preparation method for meptazinol impurity C | WEIHAI DISU PHARMACEUTICAL CO LTD | 2016-01-13 | — | — | CN | disclosed |