Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL28048768

C=C(C)C(=O)OCC(C)O.C=CC(=O)OCC

nearest known ligand 0.53

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.53
THRB P10828 2/20 0.42
HPGD P15428 1/20 0.40
ALDH1A1 P00352 5/20 0.39
NPSR1 Q6W5P4 1/20 0.37
MAPT P10636 1/20 0.36
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
CYP3A4 P08684 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
GLO1 Q04760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Ethyl Ester SCHEMBL8415514 0.94 TSHR (0.51) TSHRTHRBHPGDALDH1A1NPSR1
SCHEMBL3273928 0.92 TSHR (0.58) TSHRTHRBHPGDALDH1A1MAPT
Diethyl Maleate SCHEMBL28327398 0.90 TSHR (0.53) TSHRTHRBALDH1A1NPSR1MAPT
SCHEMBL3632671 0.88 TSHR (0.62) TSHRTHRBALDH1A1NPSR1MAPT
Acrylic Acid Ethyl Ester SCHEMBL669169 0.86 THRB (0.50) TSHRTHRBHPGDALDH1A1NPSR1
Acrylic Acid Ethyl Ester SCHEMBL28072439 0.86 TSHR (0.64) TSHRTHRBHPGDALDH1A1NPSR1
Acrylic Acid Methyl Ester SCHEMBL28153902 0.85 TSHR (0.55) TSHRTHRBHPGDALDH1A1MAPT
SCHEMBL10602461 0.84 TSHR (0.58) TSHRTHRBHPGDALDH1A1MAPT
SCHEMBL9695772 0.84 TSHR (0.72) TSHRTHRBALDH1A1MAPTHSD17B10
SCHEMBL19017 0.84 TSHR (0.72) TSHRTHRBALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459531-B Adhesive sheet and use thereof NITTO DENKO CORP. (JP) 2016-05-18 CN disclosed