⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947377 | 0.97 | — | — | |
| SCHEMBL316645 | 0.97 | — | — | |
| SCHEMBL30001725 | 0.77 | — | — | |
| SCHEMBL627795 | 0.77 | — | — | |
| SCHEMBL8375145 | 0.75 | LMNA (0.44) | — | |
| SCHEMBL2283975 | 0.73 | — | — | |
| SCHEMBL1203743 | 0.73 | — | — | |
| SCHEMBL7670567 | 0.72 | — | — | |
| SCHEMBL31064872 | 0.70 | AXL (0.41) | — | |
| Bromide SCHEMBL20854689 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189515-A | Furopyridines as bromodomain inhibitors | GLAXOSMITHKLINE IP NO 2 LTD | 2015-12-23 | — | — | CN | disclosed |