SCHEMBL28048796

SCHEMBL28048796

NC(=O)CC[C@H](Nc1n[nH]c(-c2ccccc2)n1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.58
ADORA3 P0DMS8 15/20 0.52
ADORA2A P29274 14/20 0.52
ADORA1 P30542 7/20 0.52
F2 P00734 2/20 0.50
F12 P00748 2/20 0.50
KMT2A Q03164 1/20 0.47
MMP2 P08253 2/20 0.46
MMP9 P14780 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32690195 0.74 CYP1A2 (1.00) CYP1A2ADORA3ADORA2AADORA1F2
SCHEMBL32690194 0.74 CYP1A2 (1.00) CYP1A2ADORA3ADORA2AADORA1F2
SCHEMBL3448327 0.73 KMT2A (0.64) KMT2AMMP2MMP9
SCHEMBL3448329 0.73 KMT2A (0.64) KMT2AMMP2MMP9
Hydrochloric Acid SCHEMBL23834278 0.72 KMT2A (0.62) KMT2AMMP2MMP9
SCHEMBL5744197 0.69 NPC1 (0.47) KMT2AMMP2MMP9
SCHEMBL5595918 0.69 KMT2A (0.51) KMT2AMMP2MMP9
SCHEMBL20840361 0.69 KMT2A (0.51) KMT2AMMP2MMP9
SCHEMBL9294202 0.69 KMT2A (0.51) KMT2AMMP2MMP9
SCHEMBL20189708 0.69 KMT2A (0.51) CYP1A2KMT2AMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105131058-A 3- glucamine-5-phenyl-1,2,4-triazole derivative and preparation method and uses thereof UNIV HANGZHOU NORMAL 2015-12-09 CN disclosed
CN-105131058-A 3- glucamine-5-phenyl-1,2,4-triazole derivative and preparation method and uses thereof UNIV HANGZHOU NORMAL 2015-12-09 CN disclosed