Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30978460 | 0.81 | MAPK1 (0.65) | KDM4EALDH1A1MAPK1L3MBTL1NPC1 | |
| SCHEMBL109364 | 0.81 | MAPK1 (0.65) | KDM4EALDH1A1MAPK1L3MBTL1NPC1 | |
| SCHEMBL28020808 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1MAPK1ADORA3L3MBTL1 | |
| SCHEMBL28048179 | 0.78 | MAPK1 (0.43) | KDM4EALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL15932170 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1MAPK1ADORA3L3MBTL1 | |
| SCHEMBL16179277 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1MAPK1ADORA3L3MBTL1 | |
| SCHEMBL31407736 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL1808295 | 0.77 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPK1MEN1NPC1 | |
| SCHEMBL645688 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL28934033 | 0.77 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPK1ADORA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492386-B | Novel compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS N.V. (BE) | 2016-03-09 | — | — | CN | disclosed |