Known targets — ChEMBL curated mechanism
ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL163103 | 1.00 | LMNA (0.91) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL31213259 | 1.00 | LMNA (0.91) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL1457856 | 1.00 | LMNA (0.91) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Lithium Ion SCHEMBL1458069 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL28027050 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL16029799 | 0.98 | LMNA (0.95) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL19973172 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Lithium Ion SCHEMBL1458070 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL16030009 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL23567041 | 0.95 | LMNA (0.91) | LMNAPDE4AL3MBTL1TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272847-A | Lithium gluconate preparation method | LUAN GUANGSHENG | 2016-01-27 | — | — | CN | disclosed |
| CN-104108712-B | A kind of boron doped graphene and preparation method thereof | SHENZHEN CAPCHEM TECHNOLOGY CO.，LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-104108712-A | Boron-doped graphene and preparation method thereof | SHENZHEN CAPCHEM TECHNOLOGY CO LTD | 2014-10-22 | — | — | CN | disclosed |