SCHEMBL28049322

SCHEMBL28049322

CC(C)(C)c1cc(-c2cccc3c2C=C(C2CC2)[CH]3)cc(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 2/20 0.34
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
HTR1A P08908 1/20 0.31
HTR7 P34969 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4469495 0.83 PTAFR (0.38) PTAFR
SCHEMBL4471130 0.82 PTAFR (0.37) PTAFR
SCHEMBL1241864 0.79 RXRB (0.36) PTAFRRXRARXRB
SCHEMBL1238964 0.78 RXRA (0.33) PTAFRRXRARXRB
SCHEMBL28198733 0.77 RXRB (0.35) PTAFRRXRARXRB
SCHEMBL28860851 0.77 RXRB (0.35) PTAFRRXRARXRB
SCHEMBL1241807 0.76 PTAFR (0.36) PTAFRRXRARXRB
SCHEMBL28190399 0.74 RXRA (0.33) PTAFRRXRARXRB
SCHEMBL19644561 0.74 RXRA (0.33) PTAFRRXRARXRB
SCHEMBL28723793 0.74 RXRA (0.33) PTAFRRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105358589-B Metallocene and by its derivative carbon monoxide-olefin polymeric 埃克森美孚化学专利公司 2018-07-03 CN disclosed
CN-105829326-A Bridged bis (indenyl) transition metal complexes, their preparation and use 埃克森美孚化学专利公司 2016-08-03 CN disclosed
CN-105358589-A Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEM PATENTS INC 2016-02-24 CN disclosed