Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913568 | 0.79 | LOXL2 (0.50) | LOXL2F10ABATHDAC3HDAC6 | |
| Methyl Alcohol SCHEMBL22528993 | 0.76 | ABAT (0.67) | LOXL2F10ABATHDAC3HDAC6 | |
| SCHEMBL28031818 | 0.76 | HDAC3 (0.47) | LOXL2F10ABATHDAC3HDAC6 | |
| SCHEMBL27528867 | 0.76 | LOXL2 (0.47) | LOXL2F10ABATHDAC3HDAC6 | |
| SCHEMBL27499995 | 0.75 | LOXL2 (0.56) | LOXL2F10ABATHDAC3HDAC6 | |
| SCHEMBL27773576 | 0.74 | LOXL2 (0.50) | LOXL2F10ABATHDAC3HDAC6 | |
| SCHEMBL27527368 | 0.73 | LOXL2 (0.54) | LOXL2F10ABATHDAC3HDAC6 | |
| SCHEMBL15828 | 0.72 | HRH3 (0.79) | LOXL2F10ABATHRH3NOS3 | |
| SCHEMBL27238704 | 0.72 | HRH3 (0.79) | LOXL2F10ABATHRH3NOS3 | |
| SCHEMBL7131616 | 0.72 | CYP19A1 (0.48) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272962-A | Synthetic method of 1,3-dithiane structure-containing polysubstituted olefin derivatives | UNIV LANZHOU | 2016-01-27 | — | — | CN | disclosed |