Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173670 | 0.77 | KDM4E (0.47) | CYP2C9POLBESR1STAT3SMN1; SMN2 | |
| SCHEMBL27565184 | 0.77 | PDE4A (0.41) | POLBSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL1543745 | 0.76 | CYP2C9 (0.39) | CYP2C9POLBESR1STAT3SMN1; SMN2 | |
| SCHEMBL16598146 | 0.74 | KDM4E (0.47) | CYP2C9POLBESR1STAT3SMN1; SMN2 | |
| SCHEMBL28168957 | 0.70 | KDM4C (0.53) | CYP2C9POLBMAPK8ADRA2AADRA2B | |
| SCHEMBL28168958 | 0.70 | MBOAT4 (0.45) | CYP2C9POLBESR1STAT3SMN1; SMN2 | |
| SCHEMBL2308742 | 0.70 | CYP2C9 (0.53) | CYP2C9POLBSMN1; SMN2MAPK8ADRA2A | |
| SCHEMBL9539329 | 0.70 | PIK3CD (0.43) | CYP2C9POLBESR1STAT3SMN1; SMN2 | |
| SCHEMBL17397529 | 0.69 | MAPK8 (0.43) | CYP2C9POLBESR1STAT3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28152222 | 0.69 | CYP2C9 (0.51) | CYP2C9POLBSMN1; SMN2MAPK8ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102369188-B | As the replacement niacinamide of KCNQ2/3 conditioning agent | GRUNENTHAL GMBH (DE) | 2016-03-02 | — | — | CN | disclosed |