Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.40 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825739 | 0.84 | TRPC3 (0.44) | MAPTPTGS1ALDH1A1TSHRSTIM1 | |
| SCHEMBL17064591 | 0.81 | NPY5R (0.50) | POLBMAPTPTGS1SCN9AKLKB1 | |
| SCHEMBL14996588 | 0.81 | NPY5R (0.54) | SCN9AHPGDNPY5R | |
| SCHEMBL31067434 | 0.81 | NPY5R (0.50) | POLBMAPTPTGS1SCN9AKLKB1 | |
| SCHEMBL21023817 | 0.81 | NPY5R (0.48) | POLBMAPTPTGS1SCN9AKLKB1 | |
| SCHEMBL30474516 | 0.81 | MAPT (0.45) | POLBMAPTALDH1A1HPGD | |
| SCHEMBL3160401 | 0.81 | MAPT (0.45) | POLBMAPTALDH1A1HPGD | |
| SCHEMBL25541066 | 0.79 | CRACR2A (0.52) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL4666357 | 0.79 | PTGS1 (0.63) | POLBMAPTPTGS1KDM4EALDH1A1 | |
| SCHEMBL29863856 | 0.77 | MAPT (0.39) | MAPTPTGS1SCN9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188380-B | LXR conditioning agents | 百时美施贵宝公司 | 2017-08-15 | — | — | CN | disclosed |
| CN-105188380-A | LXR modulators | BRISTOL MYERS SQUIBB CO | 2015-12-23 | — | — | CN | disclosed |