Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160401 | 1.00 | MAPT (0.45) | MAPTALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL25541040 | 0.83 | EPHX2 (0.39) | MAPTALDH1A1GAAHPGDLMNA | |
| SCHEMBL15362174 | 0.81 | MAPT (0.57) | MAPTALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL28049609 | 0.81 | POLB (0.43) | MAPTALDH1A1HPGDPOLB | |
| SCHEMBL18055499 | 0.78 | MAPT (0.64) | MAPTALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL11969682 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL8338087 | 0.78 | ALDH1A1 (0.69) | MAPTALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL13359851 | 0.76 | FGFR1 (0.41) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL964125 | 0.75 | MAPK1 (0.66) | MAPTALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL20153722 | 0.75 | NPC1 (0.50) | MAPTALDH1A1L3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-B | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2023-04-18 | — | — | CN | disclosed |