Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.60 |
| ▸ | TNKS | O95271 | 5/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.54 |
| ▸ | PARP1 | P09874 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GPR183 | P32249 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18228223 | 0.90 | SLC18A3 (0.60) | SLC18A3TNKSTNKS2PARP1POLB | |
| SCHEMBL9980757 | 0.84 | GPR119 (0.62) | SLC18A3TNKSTNKS2PARP1KMT2A | |
| SCHEMBL28134988 | 0.81 | SLC18A3 (0.60) | SLC18A3TNKSTNKS2PARP1POLB | |
| SCHEMBL28853734 | 0.81 | SLC18A3 (0.57) | SLC18A3TNKSTNKS2PARP1POLB | |
| SCHEMBL28226807 | 0.81 | SLC18A3 (0.57) | SLC18A3TNKSTNKS2PARP1POLB | |
| SCHEMBL16446856 | 0.80 | POLB (0.53) | SLC18A3TNKSTNKS2PARP1POLB | |
| SCHEMBL9980865 | 0.80 | SLC18A3 (0.55) | SLC18A3TNKSTNKS2PARP1NNMT | |
| SCHEMBL28853735 | 0.79 | SLC18A3 (0.55) | SLC18A3TNKSTNKS2PARP1POLB | |
| SCHEMBL4962237 | 0.79 | POLB (0.78) | SLC18A3POLBALDH1A1LMNAHSD11B1 | |
| Hydrochloric Acid SCHEMBL16432204 | 0.78 | MEN1 (0.56) | SLC18A3TNKSTNKS2PARP1NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392784-A | Oxoquinazolinyl-butanamide derivatives | MERCK PATENT GMBH | 2016-03-09 | — | — | CN | disclosed |