Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 12/20 | 0.72 |
| ▸ | CHUK | O15111 | 8/20 | 0.55 |
| ▸ | IKBKB | O14920 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177507 | 0.84 | LRRK2 (1.00) | LRRK2CHUKIKBKB | |
| SCHEMBL16178112 | 0.83 | LRRK2 (1.00) | LRRK2CHUKIKBKB | |
| SCHEMBL28049908 | 0.82 | LRRK2 (0.79) | LRRK2CHUKIKBKB | |
| SCHEMBL16177465 | 0.71 | LRRK2 (0.63) | LRRK2CHUKIKBKB | |
| SCHEMBL16178131 | 0.71 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL16186396 | 0.70 | LRRK2 (0.64) | LRRK2CHUKIKBKB | |
| SCHEMBL16368530 | 0.70 | CYP19A1 (0.56) | — | |
| SCHEMBL3575954 | 0.69 | LRRK2 (0.67) | LRRK2CHUKIKBKB | |
| Hydrochloric Acid SCHEMBL16343426 | 0.69 | CYP19A1 (0.54) | — | |
| SCHEMBL3568836 | 0.66 | LRRK2 (0.67) | LRRK2CHUKIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263930-A | Arylpyrrolopyridine derived compounds as lrrk2 inhibitors | LUNDBECK & CO AS H | 2016-01-20 | — | — | CN | claimed |
| CN-105263930-A | Arylpyrrolopyridine derived compounds as lrrk2 inhibitors | LUNDBECK & CO AS H | 2016-01-20 | — | — | CN | disclosed |