SCHEMBL28050290

SCHEMBL28050290

C=CSC=C.C=Cc1c2ccccc2c(C=C)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36
GPR3 P46089 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PADI4 Q9UM07 1/20 0.32
AHR P35869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29925960 0.87 ALDH1A1 (0.45) ALDH1A1TSHRGPR3HSD17B10PADI4
SCHEMBL5831187 0.87 ALDH1A1 (0.45) ALDH1A1TSHRGPR3HSD17B10PADI4
SCHEMBL28050291 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL18931271 0.78 ALDH1A1 (0.43) ALDH1A1TSHRGPR3HSD17B10PADI4
SCHEMBL19512835 0.78 ALDH1A1 (0.43) ALDH1A1TSHRGPR3HSD17B10PADI4
SCHEMBL7765395 0.75 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10PADI4
SCHEMBL7038228 0.75 PADI4 (0.52) ALDH1A1TSHRHSD17B10PADI4
SCHEMBL28005234 0.75 ALDH1A1 (0.36) ALDH1A1TSHRPADI4
SCHEMBL4646101 0.75 TSHR (0.40) ALDH1A1TSHRHSD17B10PADI4AHR
SCHEMBL31488756 0.75 TSHR (0.40) ALDH1A1TSHRHSD17B10PADI4AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294975-A Method for improving heat resistance of polyurethane resin optical material YELLOW RIVER DELTA JINGBO RES INST CHEMICAL IND CO LTD 2016-02-03 CN disclosed