Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | GUSB | P08236 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19032597 | 0.84 | ALDH1A1 (0.46) | — | |
| SCHEMBL17669644 | 0.81 | CYP1A2 (0.39) | — | |
| SCHEMBL17669642 | 0.81 | CYP1A2 (0.39) | — | |
| SCHEMBL25340168 | 0.80 | GAA (0.41) | GAA | |
| SCHEMBL18670682 | 0.80 | GAA (0.41) | GAA | |
| SCHEMBL19040783 | 0.79 | CYP4F2 (0.32) | GBA1 | |
| SCHEMBL11631537 | 0.73 | GAA (0.42) | GAAGBA1 | |
| SCHEMBL15662213 | 0.72 | TSHR (0.47) | — | |
| SCHEMBL28316297 | 0.72 | TSHR (0.47) | — | |
| SCHEMBL28008290 | 0.72 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408330-A | Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-16 | — | — | CN | disclosed |