Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006519 | 0.88 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MMP1MMP13CYP3A4 | |
| SCHEMBL27956316 | 0.83 | BTK (0.49) | ALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL17062184 | 0.81 | GAA (0.50) | ALDH1A1L3MBTL1MMP1MMP13CYP3A4 | |
| SCHEMBL16759341 | 0.81 | GAA (0.50) | ALDH1A1L3MBTL1MMP1MMP13CYP3A4 | |
| SCHEMBL3488361 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1L3MBTL1CYP3A4CYP2C19KMT2A | |
| SCHEMBL16485924 | 0.79 | KMT2A (0.53) | ALDH1A1L3MBTL1CYP3A4CYP2C19KMT2A | |
| SCHEMBL3488893 | 0.79 | KMT2A (0.56) | ALDH1A1L3MBTL1CYP3A4CYP2C19KMT2A | |
| SCHEMBL22488324 | 0.79 | KDM4E (0.53) | KMT2A | |
| SCHEMBL22468572 | 0.79 | KDM4E (0.53) | KMT2A | |
| SCHEMBL16485861 | 0.78 | GAA (0.50) | ALDH1A1L3MBTL1MMP1MMP13CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408330-A | Novel aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-16 | — | — | CN | disclosed |