Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 7/20 | 0.72 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.61 |
| ▸ | AXL | P30530 | 2/20 | 0.59 |
| ▸ | CDC7 | O00311 | 1/20 | 0.59 |
| ▸ | PLK4 | O00444 | 1/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | PAK4 | O96013 | 1/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.59 |
| ▸ | INSR | P06213 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723009 | 0.93 | MAP3K11 (0.83) | MAP3K11CAMKK2AXLCDC7PLK4 | |
| SCHEMBL28050402 | 0.91 | MAP3K11 (0.86) | MAP3K11ABL1INSRCDK2FLT3 | |
| SCHEMBL28033149 | 0.87 | MAP3K11 (0.55) | MAP3K11CAMKK2AXLMAPK1TNIK | |
| SCHEMBL722116 | 0.84 | MAP3K11 (1.00) | MAP3K11AURKAROCK2ABL1NTRK1 | |
| SCHEMBL723895 | 0.84 | MAP3K11 (1.00) | MAP3K11AURKAROCK2ABL1NTRK1 | |
| SCHEMBL721840 | 0.82 | MAP3K11 (0.83) | MAP3K11ABL1INSRCDK2FLT3 | |
| SCHEMBL15154839 | 0.81 | MAP3K11 (0.85) | MAP3K11AURKAROCK2ABL1NTRK1 | |
| SCHEMBL28050406 | 0.81 | TNIK (0.73) | MAP3K11ABL1INSRCDK2MAPK1 | |
| SCHEMBL12067580 | 0.80 | TNIK (0.72) | MAP3K11AURKAROCK2ABL1NTRK1 | |
| SCHEMBL28033172 | 0.78 | TNIK (0.70) | MAP3K11AURKAROCK2ABL1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153994-B | Bicyclic heteroaryl kinase inhibitor and using method | UNIVERSITY OF ROCHESTER (US) | 2016-02-10 | — | — | CN | disclosed |