Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057522 | 0.77 | HTR2C (0.70) | HTR2CKITAXLMKNK1MKNK2 | |
| SCHEMBL1601717 | 0.77 | HTR2C (0.70) | HTR2CKITAXLMKNK1MKNK2 | |
| SCHEMBL12789863 | 0.76 | HTR2C (0.65) | HTR2CKITAXLMKNK1MKNK2 | |
| SCHEMBL1601613 | 0.76 | HTR2C (1.00) | HTR2CLMNAHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL29360192 | 0.76 | HTR2C (0.68) | HTR2CLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL190521 | 0.76 | HTR2C (0.68) | HTR2CLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL14107782 | 0.75 | HTR2C (0.63) | HTR2CHSD17B10ALDH1A1KITHRH4 | |
| SCHEMBL14083387 | 0.75 | HTR2C (0.63) | HTR2CLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL31337089 | 0.73 | HTR2C (0.65) | HTR2CKITAXLMKNK1MKNK2 | |
| SCHEMBL4193100 | 0.73 | HTR2C (0.65) | HTR2CKITAXLMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103893183-B | 1-(2-chlorphenyl)-4-{ thieno [3,2-d] pyrimidine-4-yl } diethylenediamine compound applies preparing in anti-HIV-1 virus drugs | Guangzhou Zhongheng Electronic Technology Co.,Ltd. (CN) | 2016-02-10 | — | — | CN | disclosed |