Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875714 | 0.81 | TSHR (0.69) | TSHRCYP1A2ALDH1A1HSD17B10ERN1 | |
| SCHEMBL11443072 | 0.80 | TSHR (0.58) | TSHRCYP1A2ALDH1A1HSD17B10ERN1 | |
| SCHEMBL2948396 | 0.79 | TSHR (0.56) | TSHRCYP1A2ALDH1A1HSD17B10ERN1 | |
| SCHEMBL499283 | 0.77 | TSHR (0.50) | TSHRCYP1A2ALDH1A1HSD17B10ERN1 | |
| SCHEMBL7662054 | 0.76 | TSHR (0.61) | TSHRCYP1A2ALDH1A1HSD17B10ERN1 | |
| SCHEMBL29220999 | 0.74 | MAPT (0.50) | TSHRALDH1A1HSD17B10ERN1CDC25B | |
| SCHEMBL9096992 | 0.72 | ALDH1A1 (0.71) | TSHRALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL1250912 | 0.72 | TSHR (0.59) | TSHRCYP1A2ALDH1A1HSD17B10CDC25B | |
| SCHEMBL7461099 | 0.71 | TSHR (0.69) | TSHRCYP1A2ALDH1A1HSD17B10CDC25B | |
| Diethyl Phthalate SCHEMBL22296 | 0.71 | TSHR (1.00) | TSHRCYP1A2ALDH1A1HSD17B10CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906741-B | Aminoalkyl substituted N-thienylbenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2016-01-20 | — | — | CN | disclosed |