Quinoxaline

Quinoxaline

SCHEMBL28050792

[Cd].c1c[nH]nn1.c1ccc2nccnc2c1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MAPK1 P28482 1/20 0.34
NCF1 P14598 1/20 0.32
CCNB2 O95067 2/20 0.32
CDK1 P06493 2/20 0.32
CCNB1 P14635 2/20 0.32
GSK3B P49841 2/20 0.32
CDK5 Q00535 2/20 0.32
CDK5R1 Q15078 2/20 0.32
CCNB3 Q8WWL7 2/20 0.32
GSK3A P49840 1/20 0.32
MAPT P10636 2/20 0.31
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoxaline SCHEMBL3988599 0.98 ALDH1A1 (0.38) ALDH1A1MAPK1NCF1CCNB2CDK1
SCHEMBL28022074 0.89 ALDH1A1 (0.43) ALDH1A1MAPTKDM4EMEN1POLB
Phenazine SCHEMBL28755089 0.83 MAPT (0.50) ALDH1A1MAPTKDM4EMEN1USP2
Phenazine SCHEMBL28755011 0.83 MAPT (0.50) ALDH1A1MAPTKDM4EMEN1USP2
Quinoline SCHEMBL14977039 0.82 ALDH1A1 (0.63) ALDH1A1MAPTKDM4EMEN1POLB
Quinoline SCHEMBL27314055 0.81 ALDH1A1 (0.61) ALDH1A1MAPTKDM4EMEN1POLB
Naphthalene SCHEMBL28007049 0.80 CYP2A6 (0.38) ALDH1A1
Naphthalene SCHEMBL4047989 0.78 CYP2A6 (0.40) ALDH1A1MAPTKDM4EMEN1KMT2A
Naphthalene SCHEMBL28993985 0.78 CYP2A6 (0.40) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL28006138 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105175437-A Triazole quinoxaline cadmium complex and preparation method thereof UNIV NANYANG NORMAL 2015-12-23 CN claimed
CN-105175437-A Triazole quinoxaline cadmium complex and preparation method thereof UNIV NANYANG NORMAL 2015-12-23 CN disclosed
CN-105175437-A Triazole quinoxaline cadmium complex and preparation method thereof UNIV NANYANG NORMAL 2015-12-23 CN disclosed
CN-105175437-A Triazole quinoxaline cadmium complex and preparation method thereof UNIV NANYANG NORMAL 2015-12-23 CN disclosed