Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28050809 | 0.92 | HDAC8 (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL1227487 | 0.91 | CYP3A4 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| Potassium SCHEMBL11350259 | 0.89 | CYP3A4 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL11350253 | 0.89 | CYP3A4 (0.50) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL28825834 | 0.83 | RXRB (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| Ethylenediamine SCHEMBL10783198 | 0.81 | CYP3A4 (0.49) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| Biphenyl SCHEMBL27925618 | 0.80 | KDM4E (0.49) | POLBKDM4EHDAC4HDAC2HDAC8 | |
| Biphenyl SCHEMBL27984932 | 0.79 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL10424891 | 0.78 | SMN1; SMN2 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL11649442 | 0.77 | CYP3A4 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175596-A | Method for catalyzing copolymerization of ethylene and norbornene | UNIV TIANJIN | 2015-12-23 | — | — | CN | disclosed |