Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL23243538 | 0.89 | MEN1 (0.46) | MEN1KMT2ATSHR | |
| Dimethyl Sulfoxide SCHEMBL28338148 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHR | |
| Dimethyl Sulfoxide SCHEMBL28043357 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHR | |
| Dimethyl Sulfoxide SCHEMBL28340492 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHR | |
| Dimethyl Sulfoxide SCHEMBL5835774 | 0.82 | MEN1 (0.46) | MEN1KMT2ATSHR | |
| Dimethyl Sulfoxide SCHEMBL28041846 | 0.73 | — | — | |
| SCHEMBL1309105 | 0.73 | — | — | |
| SCHEMBL23885 | 0.68 | — | — | |
| SCHEMBL28436303 | 0.68 | MEN1 (0.75) | MEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL28192857 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237579-A | Platinum complex crystal | LUO MEI | 2016-01-13 | — | — | CN | claimed |
| CN-105237579-A | Platinum complex crystal | LUO MEI | 2016-01-13 | — | — | CN | disclosed |