Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL28043357 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Dimethyl Sulfoxide SCHEMBL23243538 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Dimethyl Sulfoxide SCHEMBL28340492 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Dimethyl Sulfoxide SCHEMBL5835774 | 0.92 | MEN1 (0.46) | MEN1KMT2ATSHRCA5ACA5B | |
| Dimethyl Sulfoxide SCHEMBL28051393 | 0.82 | GUSB (0.39) | MEN1KMT2ATSHR | |
| Dimethyl Sulfoxide SCHEMBL28158799 | 0.77 | — | — | |
| SCHEMBL28436303 | 0.76 | MEN1 (0.75) | MEN1KMT2ATSHRCA5ACA5B | |
| SCHEMBL48282 | 0.76 | MEN1 (0.75) | MEN1KMT2ATSHRCA5ACA5B | |
| Methyl Alcohol SCHEMBL28220338 | 0.73 | MEN1 (0.55) | MEN1KMT2ATSHRCA5ACA5B | |
| SCHEMBL558431 | 0.71 | MEN1 (0.67) | MEN1KMT2ATSHRCA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110643354-B | Preparation method and application of tetraphenylethylene derivative/rare earth nanoparticle composite material for identifying variable-valence chromium ions | 山东大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-110643354-A | Preparation method and application of tetraphenylethylene derivative/rare earth nanoparticle composite material for identifying variable-valence chromium ions | 山东大学 | 2020-01-03 | — | — | CN | disclosed |