Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 14/20 | 0.68 |
| ▸ | FYN | P06241 | 3/20 | 0.68 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.68 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.67 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051403 | 0.89 | USP7 (0.57) | CHEK2FYNMKNK1MAP4K4 | |
| SCHEMBL28051457 | 0.88 | FYN (0.59) | CHEK2FYNMKNK1MAP4K4CHEK1 | |
| SCHEMBL12516852 | 0.87 | CHEK2 (0.88) | CHEK2FYNMKNK1MAP4K4CHEK1 | |
| SCHEMBL27902096 | 0.86 | CHEK2 (0.62) | CHEK2FYNMKNK1MAP4K4 | |
| SCHEMBL27885119 | 0.86 | USP7 (0.70) | CHEK2FYNMKNK1MAP4K4 | |
| SCHEMBL27902097 | 0.84 | FYN (0.53) | CHEK2FYNMKNK1MAP4K4 | |
| SCHEMBL17011909 | 0.83 | CHEK2 (0.73) | CHEK2FYNMKNK1MAP4K4CHEK1 | |
| SCHEMBL27885062 | 0.83 | USP7 (0.50) | CHEK2FYNMKNK1MAP4K4 | |
| SCHEMBL27885050 | 0.83 | MAP4K4 (0.60) | CHEK2FYNMKNK1MAP4K4 | |
| SCHEMBL27885129 | 0.83 | MAP4K4 (0.52) | CHEK2FYNMKNK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812006-B | Novel antimalaria reagent | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2016-01-20 | — | — | CN | claimed |
| CN-102812006-B | Novel antimalaria reagent | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2016-01-20 | — | — | CN | disclosed |