SCHEMBL2805142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2806557	0.91	HDAC3 (0.42)	HDAC1HDAC6HDAC3HDAC2CYP1A2
	SCHEMBL2806554	0.91	HDAC3 (0.42)	HDAC1HDAC6HDAC3HDAC2CYP1A2
	SCHEMBL2802255	0.89	CYP1A2 (0.43)	CYP1A2CYP3A4CYP2C19GAAALDH1A1
	SCHEMBL2802649	0.87	NPY5R (0.43)	HDAC1HDAC6HDAC3HDAC2CYP1A2
	SCHEMBL2802647	0.87	NPY5R (0.43)	HDAC1HDAC6HDAC3HDAC2CYP1A2
	SCHEMBL2805032	0.86	MEN1 (0.41)	HDAC1HDAC6HDAC3HDAC2CYP1A2
	SCHEMBL2807824	0.86	HTT (0.40)	CYP3A4CYP2C19GAAALDH1A1HPGD
	SCHEMBL2802862	0.86	CCNA2 (0.43)	HDAC1HDAC6TSHRCCNA2CDK2
	SCHEMBL2802169	0.86	MAPT (0.43)	GAAALDH1A1HPGDKDM4ECCNA2
	SCHEMBL2807832	0.85	PKM (0.42)	CYP1A2CYP3A4ALDH1A1NPY5RUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.