Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.40 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethylbenzene SCHEMBL27935510 | 0.86 | LMNA (0.47) | APPGAAHPGDMAPK1LMNA | |
| Trifluoromethylbenzene SCHEMBL28051488 | 0.82 | KDM4E (0.54) | APPGAAHPGDMAPK1MAPT | |
| SCHEMBL8218591 | 0.81 | LMNA (0.50) | GAAMAPK1LMNAL3MBTL1MEN1 | |
| Trifluoromethylbenzene SCHEMBL27916783 | 0.79 | LMNA (0.50) | IDH2APPHPGDMAPK1LMNA | |
| Trifluoromethylbenzene SCHEMBL28051499 | 0.77 | KDM4E (0.58) | IDH2GAALMNAL3MBTL1MAPT | |
| SCHEMBL28051482 | 0.77 | IDH2 (0.54) | IDH2APPGAALMNAL3MBTL1 | |
| SCHEMBL17577090 | 0.76 | LMNA (0.45) | GAAMAPK1LMNAL3MBTL1MEN1 | |
| SCHEMBL18067373 | 0.76 | LMNA (0.45) | GAAMAPK1LMNAL3MBTL1MEN1 | |
| SCHEMBL14869402 | 0.75 | NPSR1 (0.64) | APPGAAHPGDLMNA | |
| SCHEMBL29609599 | 0.75 | NPSR1 (0.64) | APPGAAHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294588-A | Fluorotriazine-containing derivative, and preparation method and use thereof | WUHAN INST TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |