Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592430 | 0.76 | CA1 (0.55) | ALDH1A1ALOX15HSD17B10KMT2AKDM4E | |
| Ammonia Solution, Strong SCHEMBL28686299 | 0.75 | CA1 (0.53) | ALDH1A1ALOX15HSD17B10KMT2AKDM4E | |
| SCHEMBL11552940 | 0.74 | ADORA2A (0.51) | ALDH1A1ALOX15HSD17B10KMT2AKDM4E | |
| SCHEMBL15455885 | 0.74 | ALDH1A1 (0.40) | ALDH1A1ALOX15HSD17B10KMT2AKDM4E | |
| SCHEMBL12681340 | 0.73 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10KMT2AKDM4E | |
| SCHEMBL10638809 | 0.73 | ALDH1A1 (0.44) | ALDH1A1ALOX15HSD17B10KMT2AKDM4E | |
| SCHEMBL11475587 | 0.73 | KDM4E (0.52) | ALDH1A1HSD17B10KMT2AKDM4EMEN1 | |
| SCHEMBL25926428 | 0.73 | KDM4E (0.42) | ALDH1A1HSD17B10KMT2AKDM4EMEN1 | |
| SCHEMBL17185709 | 0.73 | KDM4E (0.43) | ALDH1A1HSD17B10KMT2AKDM4EMEN1 | |
| SCHEMBL5618619 | 0.73 | PDE9A (0.51) | ALDH1A1ALOX15HSD17B10KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112358459-B | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-112358459-A | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-110894192-A | Preparation method of benzofuran compound | 心远(广州)药物研究有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-105399710-A | A synthetic method of 2-phenyl-3-cyano benzofuran compounds | UNIV ZHEJIANG | 2016-03-16 | — | — | CN | disclosed |
| CN-105399710-A | A synthetic method of 2-phenyl-3-cyano benzofuran compounds | UNIV ZHEJIANG | 2016-03-16 | — | — | CN | disclosed |