Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703302 | 0.81 | MEN1 (0.82) | MEN1KMT2AMAPTTDO2TDP1 | |
| SCHEMBL13699679 | 0.80 | NPC1 (0.55) | MEN1KMT2AMAPTTDO2TDP1 | |
| SCHEMBL2433951 | 0.76 | MAPT (0.58) | MEN1KMT2AMAPTTDO2TDP1 | |
| Dibenzofuran SCHEMBL28066911 | 0.74 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL483262 | 0.74 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5332842 | 0.72 | MAPT (0.63) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL22410653 | 0.71 | IDO1 (0.53) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL2190235 | 0.71 | MAPT (0.60) | MEN1KMT2AMAPTTDP1NPC1 | |
| SCHEMBL9187802 | 0.71 | MEN1 (0.60) | MEN1KMT2AMAPTTDO2TDP1 | |
| SCHEMBL4246750 | 0.70 | AKR1B1 (0.61) | MEN1KMT2AMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209449-A | Inhibitors of the kynurenine pathway | CURADEV PHARMA PRIVATE LTD | 2015-12-30 | — | — | CN | claimed |