Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14092257 | 0.84 | TRIM24 (0.43) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL29955862 | 0.83 | CA1 (0.44) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16238352 | 0.82 | CCR1 (0.38) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16237573 | 0.81 | CCR1 (0.37) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16055152 | 0.81 | CCR1 (0.37) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16237791 | 0.79 | CCR1 (0.36) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16237465 | 0.77 | PDE3B (0.35) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16237725 | 0.77 | CCR1 (0.34) | CCR1CCR5CCR8NPC1RAB9A | |
| SCHEMBL16238230 | 0.76 | PIM1 (0.31) | PIM1PIM2ALDH1A1 | |
| SCHEMBL16237611 | 0.76 | ALDH1A1 (0.35) | CCR1CCR5CCR8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-105209449-A | Inhibitors of the kynurenine pathway | CURADEV PHARMA PRIVATE LTD | 2015-12-30 | — | — | CN | disclosed |