SCHEMBL28052040

SCHEMBL28052040

Cc1nccnc1-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 1/20 0.54
KMT2A Q03164 1/20 0.54
KIF11 P52732 3/20 0.50
TRPV1 Q8NER1 11/20 0.44
TSHR P16473 1/20 0.43
HTR1D P28221 1/20 0.41
ADRA1A P35348 1/20 0.41
NISCH Q9Y2I1 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
DGAT1 O75907 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12320156 0.82 KIF11 (0.50) KIF11TRPV1NISCH
SCHEMBL10263741 0.79 TDP1 (0.42) KDM4EALDH1A1KMT2ATRPV1NISCH
SCHEMBL15125568 0.78 KIF11 (0.54) KDM4EALDH1A1KMT2AKIF11
SCHEMBL12320567 0.75 MAPK14 (0.44)
SCHEMBL29536871 0.75 ABL1 (0.35) KDM4EALDH1A1KMT2A
SCHEMBL15730888 0.75 CCNB2 (0.43) KDM4EALDH1A1KMT2ATRPV1NPC1
SCHEMBL29299450 0.74 KDM4E (0.49) KDM4EALDH1A1KMT2AKIF11TRPV1
SCHEMBL14525857 0.74 KDM4E (0.53) KDM4EALDH1A1KMT2AKIF11TRPV1
SCHEMBL11947319 0.74 KDM4E (0.49) KDM4EALDH1A1KMT2AKIF11TRPV1
SCHEMBL2910139 0.74 PTGS1 (0.43) KDM4EALDH1A1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105418686-A Pyrazine phosphorescent iridium complex, preparation method and application thereof CHINA BEIJING BEIDA JUBANG SCIENCE & TECH CO LTD 2016-03-23 CN disclosed