SCHEMBL28052046

SCHEMBL28052046

C=CCCC#N.C=CCCC#N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
TDP1 Q9NUW8 1/20 0.44
NPSR1 Q6W5P4 1/20 0.37
TSHR P16473 5/20 0.35
LOX P28300 1/20 0.35
LOXL3 P58215 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
CYP3A4 P08684 1/20 0.35
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150486 1.00
Ammonia Solution, Strong SCHEMBL1258393 0.97
SCHEMBL28065323 0.97
Hydrochloric Acid SCHEMBL27676072 0.94
Hydrochloric Acid SCHEMBL27676073 0.94
Butadiene SCHEMBL27967344 0.94 ALDH1A1 (0.88) ALDH1A1TDP1NPSR1TSHRLOX
SCHEMBL28170729 0.91
SCHEMBL27734428 0.91 ALDH1A1 (0.83) ALDH1A1TDP1NPSR1TSHRLOX
SCHEMBL23726379 0.89 ALDH1A1 (0.79) ALDH1A1TDP1NPSR1
SCHEMBL11747353 0.89 ALDH1A1 (0.79) ALDH1A1TDP1NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502206-B For the preparation of the method for nitrile INVISTA TECHNOLOGIES S.A.R.L. (CH) 2016-01-13 CN disclosed