Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750265 | 0.85 | — | — | |
| SCHEMBL6750262 | 0.85 | — | — | |
| SCHEMBL1785020 | 0.80 | — | — | |
| SCHEMBL1785021 | 0.80 | — | — | |
| SCHEMBL5742287 | 0.79 | SOAT1 (0.33) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| SCHEMBL3616414 | 0.78 | — | — | |
| SCHEMBL3454057 | 0.78 | — | — | |
| SCHEMBL7207658 | 0.78 | — | — | |
| SCHEMBL3606097 | 0.78 | — | — | |
| SCHEMBL9815905 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837591-A | Pharmaceutical composition of alfacalcidol and medical application of pharmaceutical composition | 陈斌 | 2016-08-10 | — | — | CN | disclosed |
| CN-105481810-A | Novel Fumu lactone compounds, and preparation method and medical application thereof | WU JINFENG | 2016-04-13 | — | — | CN | disclosed |
| CN-105418626-A | New eremophilanolide compound as well as preparation method and medical application thereof | Xining yige intellectual property consultation service co ltd | 2016-03-23 | — | — | CN | disclosed |