Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 5/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.51 |
| ▸ | MIF | P14174 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192664 | 0.79 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1655937 | 0.78 | ESR1 (0.58) | HSD17B3APPESR1ESR2ALDH1A1 | |
| SCHEMBL62512 | 0.77 | MAPT (0.56) | MAPTAPPKDM4EMEN1KMT2A | |
| SCHEMBL62090 | 0.77 | MAPT (0.56) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL28106136 | 0.74 | MIF (0.56) | MAPTHSD17B3APPESR1ESR2 | |
| SCHEMBL17536884 | 0.74 | MAPT (1.00) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL29999385 | 0.74 | ESR1 (0.61) | MAPTAPPESR1ESR2KDM4E | |
| SCHEMBL17265862 | 0.74 | ESR1 (0.61) | MAPTAPPESR1ESR2KDM4E | |
| SCHEMBL28730391 | 0.73 | ALDH1A1 (0.79) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL13212103 | 0.73 | APP (0.57) | HSD17B3APPESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348214-A | Benzoxazinone thiophenol fluorescent probe and preparation method thereof | UNIV QILU TECHNOLOGY | 2016-02-24 | — | — | CN | claimed |
| CN-105348214-B | A kind of benzoxazine ketone benzenethiol fluorescence probe and preparation method thereof | 齐鲁工业大学 | 2018-02-02 | — | — | CN | disclosed |
| CN-105348214-A | Benzoxazinone thiophenol fluorescent probe and preparation method thereof | UNIV QILU TECHNOLOGY | 2016-02-24 | — | — | CN | disclosed |