Pyridine

Pyridine

SCHEMBL28052819

C#C.C#C.c1ccncc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.82
NAPRT Q6XQN6 1/20 0.82
TDP1 Q9NUW8 1/20 0.82
NOTUM Q6P988 1/20 0.37
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL712082 1.00
Pyridine SCHEMBL28030067 1.00 TSHR (0.82) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL27903857 0.96
Pyridine SCHEMBL27998799 0.96
Pyridine SCHEMBL10894927 0.91 TSHR (0.82) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL9037865 0.91 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL16 0.91
SCHEMBL3052767 0.91 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
Pyridine SCHEMBL933604 0.91 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2
Benzene SCHEMBL10751789 0.91 TSHR (1.00) TSHRNAPRTTDP1NOTUMSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112225899-A Method for preparing poly-1, 4-dithiine and polythiophene through polymerization of elemental sulfur and active internal alkyne under temperature regulation and control, mutual conversion and application 华南理工大学 2021-01-15 CN claimed
CN-113429575-A Selenium/tellurium-containing heterocyclic polymer and preparation method and conversion method thereof 华南理工大学 2021-09-24 CN disclosed
CN-108279224-B A method of persulfuric acid ion concentration is detected with conjugated polyelectrolytes-silver HUNAN NORMAL UNIVERSITY (CN) 2019-10-29 CN disclosed
CN-108976394-A Conjugated polymer, synthetic method and the method for detecting Etimicin concentration with it 湖南师范大学 2018-12-11 CN disclosed
CN-108279224-A A method of detecting persulfuric acid ion concentration with conjugated polyelectrolytes-silver 湖南师范大学 2018-07-13 CN disclosed
CN-103788370-B A kind of ultrasonic assistant prepares the method for polymer nanocomposite ball and nanometer rod without soap click polyreaction NORTHWEST A & F UNIVERSITY (CN) 2016-03-02 CN disclosed