Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.52 |
| ▸ | KLK1 | P06870 | 9/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486491 | 0.90 | KLKB1 (0.63) | KLKB1KLK1HSD17B10POLBTDP1 | |
| SCHEMBL16487112 | 0.85 | HSD17B10 (0.53) | KLKB1KLK1HSD17B10POLBTDP1 | |
| SCHEMBL19087149 | 0.83 | HSD17B10 (0.70) | KLKB1HSD17B10POLBTDP1L3MBTL1 | |
| SCHEMBL16246805 | 0.82 | KLKB1 (0.62) | KLKB1KLK1HSD17B10POLBTDP1 | |
| SCHEMBL29779641 | 0.80 | KLKB1 (0.64) | KLKB1KLK1 | |
| SCHEMBL19087151 | 0.78 | POLB (0.71) | KLKB1HSD17B10POLBTDP1L3MBTL1 | |
| SCHEMBL16487373 | 0.78 | KLKB1 (0.62) | KLKB1KLK1 | |
| SCHEMBL16487412 | 0.75 | HTT (0.62) | KLKB1KLK1HSD17B10L3MBTL1 | |
| SCHEMBL948453 | 0.74 | HSD17B10 (0.61) | KLKB1HSD17B10POLBTDP1L3MBTL1 | |
| SCHEMBL4403052 | 0.74 | MEN1 (0.52) | HSD17B10POLBHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683179-A | Inhibitors of plasma kallikrein | 卡尔维斯塔制药有限公司 | 2016-06-15 | — | — | CN | disclosed |