SCHEMBL28053016

SCHEMBL28053016

CCC(N)CCCCCOC(=O)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NAAA Q02083 1/20 0.33
S1PR2 O95136 6/20 0.33
S1PR1 P21453 6/20 0.33
S1PR3 Q99500 6/20 0.33
S1PR4 O95977 4/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
EPHX1 P07099 1/20 0.32
HTR2C P28335 1/20 0.31
ACHE P22303 2/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28484987 1.00 CES2 (0.37) CES2ALDH1A1NAAAS1PR2S1PR1
SCHEMBL28105313 1.00 CES2 (0.37) CES2ALDH1A1NAAAS1PR2S1PR1
SCHEMBL28387585 0.86 CA1 (0.32) CES2CA1CA2
SCHEMBL28627217 0.86 S1PR2 (0.45) CES2ALDH1A1NAAAS1PR2S1PR1
SCHEMBL23174985 0.83 TP53 (0.38) CES2ALDH1A1NAAAS1PR2S1PR1
SCHEMBL27742916 0.83 S1PR2 (0.45) CES2ALDH1A1S1PR2S1PR1S1PR3
SCHEMBL23850596 0.83 S1PR2 (0.45) CES2ALDH1A1S1PR2S1PR1S1PR3
SCHEMBL28718189 0.82 CA1 (0.40) CES2ALDH1A1NAAAS1PR2S1PR1
SCHEMBL12493945 0.81 TP53 (0.39) CES2ALDH1A1
SCHEMBL28038603 0.81 TP53 (0.39) CES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103717571-B The tetracycline compound that 9-amino methyl replaces KBP BIOSCIENCES Co.,Ltd. (CN) 2016-01-13 CN disclosed