Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781529 | 0.86 | AOC3 (0.57) | AOC3NPSR1RAB9AALDH1A1POLB | |
| SCHEMBL17653723 | 0.84 | SLC7A5 (0.55) | AOC3NPSR1RAB9AALDH1A1POLB | |
| SCHEMBL30489996 | 0.84 | SLC7A5 (0.55) | AOC3NPSR1RAB9AALDH1A1POLB | |
| SCHEMBL10752853 | 0.84 | MEN1 (0.61) | AOC3NPSR1RAB9AALDH1A1POLB | |
| SCHEMBL12255382 | 0.84 | MTNR1B (0.56) | SIRT2BRD4RAB9AALDH1A1HPGD | |
| SCHEMBL4523190 | 0.84 | SIRT2 (0.60) | SIRT2BRD4AOC3RAB9AALDH1A1 | |
| SCHEMBL3193808 | 0.83 | SIRT2 (0.62) | SIRT2BRD4RAB9AALDH1A1HPGD | |
| SCHEMBL3929633 | 0.82 | SIRT2 (0.52) | SIRT2BRD4RAB9AALDH1A1HPGD | |
| SCHEMBL20339354 | 0.82 | SIRT2 (0.57) | SIRT2BRD4RAB9AALDH1A1HPGD | |
| SCHEMBL27399582 | 0.81 | CYP4F2 (0.54) | SIRT2BRD4RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237416-A | Synthesis method of 5-aminoindanone | Hunan huateng pharmaceutical co ltd | 2016-01-13 | — | — | CN | disclosed |