Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937101 | 0.81 | GABRA1 (0.39) | DAOGSK3BSLC6A2KDM4EMAPT | |
| SCHEMBL23362972 | 0.77 | DAO (0.39) | DAOGSK3BSLC6A2KDM4EMAPT | |
| SCHEMBL23362973 | 0.77 | DAO (0.39) | DAOGSK3BSLC6A2KDM4EMAPT | |
| SCHEMBL26664130 | 0.77 | KMT2A (0.34) | — | |
| SCHEMBL178636 | 0.74 | HTR2A (0.35) | DAOKDM4EMAPTHPGDL3MBTL1 | |
| SCHEMBL20683631 | 0.74 | TSHR (0.36) | DAOGSK3BSLC6A2HPGD | |
| SCHEMBL21495100 | 0.72 | DAO (0.35) | DAOGSK3B | |
| SCHEMBL26797050 | 0.71 | — | — | |
| SCHEMBL25425456 | 0.71 | GSK3B (0.34) | DAOGSK3BSLC6A2HPGD | |
| SCHEMBL23411290 | 0.71 | DAO (0.47) | DAOGSK3BKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |