Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline SCHEMBL27565103 | 1.00 | TSHR (0.50) | TSHRNAPRTTDP1ALDH1A1NOTUM | |
| Pyridine SCHEMBL28957933 | 0.89 | ALDH1A1 (0.52) | TSHRNAPRTTDP1ALDH1A1NOTUM | |
| Quinoxaline SCHEMBL10462492 | 0.88 | ALDH1A1 (0.50) | TSHRALDH1A1NOTUMNCF1KDM4E | |
| SCHEMBL3190528 | 0.88 | ALDH1A1 (0.55) | TSHRALDH1A1NCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL27830916 | 0.88 | ALDH1A1 (0.55) | TSHRALDH1A1NCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL27549902 | 0.85 | ALDH1A1 (0.52) | TSHRNAPRTALDH1A1NCF1KDM4E | |
| Quinoxaline SCHEMBL6928518 | 0.85 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1NCF1KDM4E | |
| Quinoxaline SCHEMBL5315 | 0.85 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1NCF1KDM4E | |
| Quinoxaline SCHEMBL29355228 | 0.85 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1NCF1KDM4E | |
| Quinoxaline SCHEMBL30320908 | 0.85 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1NCF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294742-B | Bispyridine quinoxaline ligand silver metal complex and preparation method thereof | 南阳师范学院 | 2017-05-17 | — | — | CN | disclosed |
| CN-105294742-A | Bispyridine quinoxaline ligand silver metal complex and preparation method thereof | UNIV NANYANG NORMAL | 2016-02-03 | — | — | CN | disclosed |