Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.58 |
| ▸ | ACHE | P22303 | 8/20 | 0.58 |
| ▸ | BCHE | P06276 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13582046 | 0.84 | PTGS2 (0.54) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL13582049 | 0.84 | PTGS2 (0.54) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL2580306 | 0.84 | PTGS2 (0.57) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL1062701 | 0.80 | KMT2A (0.55) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL6394314 | 0.79 | PTGS2 (0.57) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL15145397 | 0.77 | PTGS2 (0.57) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL895976 | 0.77 | PTGS2 (0.62) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL19984540 | 0.76 | PTGS2 (0.65) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL13583204 | 0.75 | PTGS2 (0.64) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL13583200 | 0.75 | PTGS2 (0.64) | PTGS2ACHEBCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102471300-B | Compositions and methods for enhancing viral potency | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2016-04-13 | — | — | CN | disclosed |