Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 16/20 | 0.73 |
| ▸ | MYC | P01106 | 1/20 | 0.58 |
| ▸ | PDE2A | O00408 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446284 | 0.84 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL16446660 | 0.81 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL16446206 | 0.81 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL28053519 | 0.81 | PROKR1 (0.79) | PROKR1 | |
| SCHEMBL16446277 | 0.81 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL21359167 | 0.77 | PROKR1 (0.62) | PROKR1MYCALDH1A1LMNAHPGD | |
| SCHEMBL7316755 | 0.77 | DRD2 (0.65) | PROKR1MYCALDH1A1LMNAHPGD | |
| SCHEMBL16445733 | 0.77 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL16446194 | 0.75 | PROKR1 (1.00) | PROKR1 | |
| SCHEMBL28053530 | 0.75 | PROKR1 (0.76) | PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | claimed |
| CN-105452233-A | Piperidine and azepane derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICALS CO | 2016-03-30 | — | — | CN | disclosed |