Butyric Acid

Butyric Acid

SCHEMBL28053652

C=CC[n+]1ccn(C)c1.CCCC(=O)[O-]

nearest known ligand 0.40

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.40
HDAC3 O15379 2/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.31
HSP90AA1 P07900 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL28053578 0.90 ALDH1A1 (0.33) ALDH1A1GAAMEN1HSP90AA1KMT2A
Acetic Acid SCHEMBL2031474 0.86 ALDH1A1 (0.35) ALDH1A1GAAMEN1HSP90AA1KMT2A
SCHEMBL17418977 0.85
SCHEMBL17418420 0.83
Propionic Acid SCHEMBL2451728 0.83 ALDH1A1 (0.30) ALDH1A1GAA
Butyric Acid SCHEMBL509159 0.83 FFAR3 (0.47) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL28779426 0.82 ALDH1A1 (0.33) ALDH1A1GAA
Methoxyacetic Acid SCHEMBL17418914 0.82 ALDH1A1 (0.31) ALDH1A1GAA
Trifluoroacetic Acid SCHEMBL4558165 0.81 ALDH1A1 (0.35) ALDH1A1GAA
SCHEMBL173392 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102928452-B A kind of assay method of imidazole type ion liquid negative ion hydrogen bond Forming ability HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-01-20 CN disclosed