Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1871815 | 0.85 | ALPL (0.33) | ALPL | |
| Oxalic Acid SCHEMBL21436329 | 0.85 | ALPL (0.33) | ALPL | |
| Succinic Acid SCHEMBL21436621 | 0.79 | EGLN1 (0.38) | ALPL | |
| Fumaric Acid SCHEMBL21436601 | 0.79 | TSHR (0.38) | ALPLALDH1A1 | |
| SCHEMBL64209 | 0.79 | — | — | |
| Cadaverine Tartrate SCHEMBL21436357 | 0.78 | TSHR (0.40) | — | |
| Hydrochloric Acid SCHEMBL3832428 | 0.77 | ALPL (0.40) | ALPL | |
| Ammonia Solution, Strong SCHEMBL21436559 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL14335493 | 0.77 | — | — | |
| Pivalate SCHEMBL27543436 | 0.77 | TSHR (0.42) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358151-A | Compounds for treating spinal muscular atrophy | HOFFMANN LA ROCHE | 2016-02-24 | — | — | CN | disclosed |