Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054062 | 1.00 | EPHX1 (0.43) | EPHX1ACP3L3MBTL1USP1WDR48 | |
| SCHEMBL8679281 | 0.84 | TYR (0.44) | ALDH1A1MAPTTYRHPGDMEN1 | |
| SCHEMBL28580561 | 0.81 | CA12 (0.40) | L3MBTL1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL28580566 | 0.79 | TYR (0.42) | EPHX1L3MBTL1AKR1C3AKR1C2SMN1; SMN2 | |
| SCHEMBL6002894 | 0.79 | ACP3 (0.42) | EPHX1ACP3USP1WDR48ALDH1A1 | |
| SCHEMBL28054154 | 0.78 | ACP3 (0.52) | EPHX1ACP3ALDH1A1MAPTTYR | |
| SCHEMBL9812362 | 0.78 | ACP3 (0.52) | EPHX1ACP3ALDH1A1MAPTTYR | |
| SCHEMBL28880782 | 0.76 | ACP3 (0.40) | EPHX1ACP3USP1WDR48ALDH1A1 | |
| SCHEMBL7922942 | 0.76 | GAA (0.41) | EPHX1ACP3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28619311 | 0.75 | POLB (0.51) | EPHX1ACP3AKR1C3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461508-B | A kind of method of the diarylethane class compound of synthesis of chiral 1,1 | 浙江大学 | 2017-09-19 | — | — | CN | disclosed |
| CN-105461508-A | A method of synthesizing chiral 1,1-diarylethane compounds | UNIV ZHEJIANG | 2016-04-06 | — | — | CN | disclosed |