Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679281 | 0.88 | TYR (0.44) | CA12CA2CA9CA1TYR | |
| SCHEMBL28054063 | 0.81 | EPHX1 (0.43) | TYRSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28054062 | 0.81 | EPHX1 (0.43) | TYRSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28580566 | 0.80 | TYR (0.42) | TYRSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL3863819 | 0.80 | KMT2A (0.45) | CA12CA2CA9CA1SMN1; SMN2 | |
| SCHEMBL27667894 | 0.80 | KMT2A (0.45) | CA12CA2CA9CA1SMN1; SMN2 | |
| SCHEMBL11288837 | 0.78 | ACHE (0.41) | TYRSMN1; SMN2LMNATSHRALOX12 | |
| SCHEMBL11208747 | 0.77 | TYR (0.42) | TYRSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11331364 | 0.77 | MEN1 (0.43) | CA12CA2CA9CA1SMN1; SMN2 | |
| SCHEMBL10720270 | 0.77 | CA12 (0.46) | CA12CA2CA9CA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |