SCHEMBL28054192

SCHEMBL28054192

OC(O)C1c2ccc(F)cc2-c2cc(F)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
PPIA P62937 3/20 0.33
ACHE P22303 2/20 0.33
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
IDO1 P14902 2/20 0.33
HSD17B2 P37059 1/20 0.33
PGR P06401 1/20 0.32
NPC1 O15118 1/20 0.32
CES2 O00748 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25508926 0.78 ACHE (0.35) CA9CA1CA2CA7ACHE
SCHEMBL27818485 0.67 PPIA (0.47) PPIAPGRPDK2
SCHEMBL23848434 0.67 ACHE (0.40) CA9CA1CA2CA7ACHE
SCHEMBL23848579 0.67 ACHE (0.40) CA9CA1CA2CA7ACHE
SCHEMBL27419379 0.65 CA1 (0.35) CA9CA1CA2CA7PPIA
SCHEMBL11857719 0.65 MEN1 (0.31) ACHE
SCHEMBL27980276 0.64 KDM1A (0.41) CA9CA1CA2CA7PPIA
SCHEMBL27818578 0.63 PPIA (0.43) PPIAPDK2
SCHEMBL22261494 0.62 ESR1 (0.44) PGRCES1
SCHEMBL7566746 0.61 ACHE (0.43) CA9CA1CA2CA7ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105384611-A Electron donor of Ziegler-Natta catalyst and preparation method of electron donor SUZHOU APAC BIOLOGICAL SCIENCE & TECH CO LTD 2016-03-09 CN disclosed