Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20703924 | 0.82 | TDP1 (0.55) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL20703925 | 0.82 | TDP1 (0.55) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL31151600 | 0.81 | TDP1 (0.72) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL6655711 | 0.81 | TDP1 (0.72) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL21216758 | 0.78 | ALDH1A1 (0.40) | TDP1L3MBTL1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3928336 | 0.78 | ALDH1A1 (0.40) | TDP1L3MBTL1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL11699791 | 0.77 | TDP1 (0.45) | TDP1L3MBTL1TSHRSMN1; SMN2GPR35 | |
| SCHEMBL27462745 | 0.76 | TDP1 (0.64) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL1585523 | 0.76 | TDP1 (1.00) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL33666 | 0.76 | TDP1 (1.00) | TDP1L3MBTL1TSHRSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717120-B | Preparation method of 3- (2-methyl-6-nitrophenyl) -4, 5-dihydro-isoxazole | 湖南海利常德农药化工有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-113717120-B | Preparation method of 3- (2-methyl-6-nitrophenyl) -4, 5-dihydro-isoxazole | 湖南海利常德农药化工有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-113717120-A | Preparation method of 3- (2-methyl-6-nitrophenyl) -4, 5-dihydroisoxazole | 湖南海利常德农药化工有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-113717120-A | Preparation method of 3- (2-methyl-6-nitrophenyl) -4, 5-dihydroisoxazole | 湖南海利常德农药化工有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-105481787-B | The preparation method of 3 (2 methyl, 6 nitrobenzophenone) 4,5 dihydro-isoxazoles | 湖南海利化工股份有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-105481787-A | Method for preparing 3-(2-methyl-6-nitrophenyl)-4,5-dihydroisoxazole | HUNAN HAILI CHEMICAL IND CO LTD | 2016-04-13 | — | — | CN | disclosed |
| CN-105481787-A | Method for preparing 3-(2-methyl-6-nitrophenyl)-4,5-dihydroisoxazole | HUNAN HAILI CHEMICAL IND CO LTD | 2016-04-13 | — | — | CN | disclosed |