Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263448 | 0.91 | KDM4E (0.37) | CREBBPKDM4ETSHRALDH1A1L3MBTL1 | |
| SCHEMBL28263450 | 0.85 | KDM4E (0.41) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL28183103 | 0.78 | HSD17B10 (0.38) | CDK8KDM4EALDH1A1MAPTALOX15 | |
| Ammonia Solution, Strong SCHEMBL28681505 | 0.76 | TSHR (0.64) | LOXL2CYP4F2CYP4A11TSHRRAB9A | |
| SCHEMBL34953 | 0.76 | TSHR (0.70) | LOXL2CYP4F2CYP4A11TSHRRAB9A | |
| SCHEMBL27956762 | 0.75 | LOXL2 (0.44) | CREBBPLOXL2CDK8CYP4F2CYP4A11 | |
| SCHEMBL8054504 | 0.74 | TSHR (0.67) | LOXL2CYP4F2CYP4A11TSHRRAB9A | |
| Ammonia Solution, Strong SCHEMBL28556515 | 0.74 | TSHR (0.67) | LOXL2CYP4F2CYP4A11TSHRRAB9A | |
| SCHEMBL29966404 | 0.74 | TSHR (0.67) | LOXL2CYP4F2CYP4A11TSHRRAB9A | |
| Methyl Alcohol SCHEMBL28469619 | 0.74 | TSHR (0.67) | LOXL2CYP4F2CYP4A11TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103239720-B | Treatment or lenitive material | SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-16 | — | — | CN | disclosed |