SCHEMBL28054337

SCHEMBL28054337

CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.61
PPARG P37231 3/20 0.61
TGM2 P21980 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
KLK7 P49862 1/20 0.48
KLK5 Q9Y337 1/20 0.48
CACNA1B Q00975 3/20 0.48
GAA P10253 1/20 0.46
CTSL P07711 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28054294 1.00 PPARA (0.61) PPARAPPARGTGM2ALDH1A1MAPT
SCHEMBL29402178 0.86 KLK7 (0.53) PPARAPPARGALDH1A1MAPTKLK7
SCHEMBL84710 0.85 PPARA (0.63) PPARAPPARGKLK7KLK5CACNA1B
SCHEMBL344669 0.85 PPARA (0.63) PPARAPPARGKLK7KLK5CACNA1B
SCHEMBL344670 0.85 PPARA (0.63) PPARAPPARGKLK7KLK5CACNA1B
SCHEMBL27770773 0.84 PPARA (0.58) PPARAPPARGALDH1A1MAPTGAA
SCHEMBL5348911 0.84 CACNA1B (0.65) PPARAPPARGALDH1A1MAPTKLK7
SCHEMBL5347155 0.84 CACNA1B (0.65) PPARAPPARGALDH1A1MAPTKLK7
SCHEMBL441283 0.84 PPARA (0.68) PPARAPPARGCTSL
SCHEMBL199415 0.84 PPARA (0.68) PPARAPPARGCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105498838-A Baeyer-Villiger oxidation reaction catalyst and preparation method and application thereof UNIV SHIJIAZHUANG 2016-04-20 CN disclosed